Quantification of Eosinophilic Granule Protein Deposition in Biopsies of Inflammatory Skin Diseases by Automated Image Analysis of Highly Sensitive Immunostaining

Eosinophilic granulocytes are major effector cells in inflammation. Extracellular deposition of toxic eosinophilic granule proteins (EGPs), but not the presence of intact eosinophils, is crucial for their functional effect in situ. As even recent morphometric approaches to quantify the involvement o...

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Bibliographic Details
Main Authors: Peter Kiehl, Katrin Falkenberg, Markus Vogelbruch, Alexander Kapp
Format: Article
Language:English
Published: Hindawi Limited 1999-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/1999/735075