Should Skin Biopsies Be Performed in Patients Suspected of Having Parkinson’s Disease?

In patients with Parkinson’s disease (PD), the molecularly misfolded form of α-synuclein was recently identified in cutaneous autonomic nerve fibers which displayed increased accumulation even in early disease stages. However, the underlying mechanisms of synucleinopathic nerve damage and its implic...

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Bibliographic Details
Main Authors: Timo Siepmann, Ana Isabel Penzlin, Ben Min-Woo Illigens, Heinz Reichmann
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2017/6064974