Circulating Irisin Is Reduced in Male Patients with Type 1 and Type 2 Myotonic Dystrophies

Circulating Irisin Is Reduced in Male Patients with Type 1 and Type 2 Myotonic Dystrophies

ContextMyotonic dystrophies (DM) are dominantly inherited muscle disorders characterized by myotonia, muscle weakness, and wasting. The reasons for sarcopenia in DMs are uncleared and multiple factors are involved. Irisin, a positive hormone regulator of muscle growth and bone, may play a role.Objec...

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Bibliographic Details
Main Authors: Elena Dozio, Elena Passeri, Rosanna Cardani, Stefano Benedini, Carmen Aresta, Rea Valaperta, Massimiliano Corsi Romanelli, Giovanni Meola, Valeria Sansone, Sabrina Corbetta
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Endocrinology
Subjects:
myotonic distrophies
myotubes
irisin
fat mass
insulin resistance
bone density
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00320/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2017.00320/full

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