Gnaz couples the circadian and dopaminergic system to G protein-mediated signaling in mouse photoreceptors.

The mammalian retina harbors a circadian clockwork that regulates vision and promotes healthiness of retinal neurons, mainly through directing the rhythmic release of the neurohormones dopamine-acting on dopamine D4 receptors-and melatonin-acting on MT1 and MT2 receptors. The gene Gnaz-a unique Gi/o...

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Bibliographic Details
Main Authors: Patrick Vancura, Shaima Abdelhadi, Erika Csicsely, Kenkichi Baba, Gianluca Tosini, P Michael Iuvone, Rainer Spessert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0187411