ApoE knockout and knockin mice: the history of their contribution to the understanding of atherogenesis
ApoE is a multifunctional protein that is expressed by many cell types that influences many aspects of cardiovascular physiology. In humans, there are three major allelic variants that differentially influence lipoprotein metabolism and risk for the development of atherosclerosis. Apoe-deficient mic...
Main Authors: | Godfrey S. Getz, Catherine A. Reardon |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520309809 |
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