Mapping allosteric communications within individual proteins
The computational prediction of protein allostery can guide experimental studies of protein function and cellular activity. Here, the authors develop a network-based method to detect allosteric coupling within proteins solely based on their structures, and set up a webserver for allostery prediction...
Main Authors: | Jian Wang, Abha Jain, Leanna R. McDonald, Craig Gambogi, Andrew L. Lee, Nikolay V. Dokholyan |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-17618-2 |
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