The Developmental Origins of Opioid Use Disorder and Its Comorbidities

The Developmental Origins of Opioid Use Disorder and Its Comorbidities

Opioid use disorder (OUD) rarely presents as a unitary psychiatric condition, and the comorbid symptoms likely depend upon the diverse risk factors and mechanisms by which OUD can arise. These factors are heterogeneous and include genetic predisposition, exposure to prescription opioids, and environ...

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Bibliographic Details
Main Authors: Sophia C. Levis, Stephen V. Mahler, Tallie Z. Baram
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Human Neuroscience
Subjects:
early life stress
opioids
addiction
sex
anhedonia
reward
Online Access:https://www.frontiersin.org/articles/10.3389/fnhum.2021.601905/full

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