Repertoire Development and the Control of Cytotoxic/Effector Function in Human γδ T Cells

Repertoire Development and the Control of Cytotoxic/Effector Function in Human γδ T Cells

T cells develop into two major populations distinguished by their T cell receptor (TCR) chains. Cells with the αβ TCR generally express CD4 or CD8 lineage markers and mostly fall into helper or cytotoxic/effector subsets. Cells expressing the alternate γδ TCR in humans generally do not express linea...

Full description

Bibliographic Details
Main Authors:	Elizabeth M. Urban, Andrei I. Chapoval, C. David Pauza
Format:	Article
Language:	English
Published:	Hindawi Limited 2010-01-01
Series:	Clinical and Developmental Immunology
Online Access:	http://dx.doi.org/10.1155/2010/732893

Similar Items

γδT cells are ADCC effectors in elite HIV controllers
by: Armstrong Cheryl, et al.
Published: (2010-05-01)

Human γδ TCR Repertoires in Health and Disease
by: Alina Suzann Fichtner, et al.
Published: (2020-03-01)

γδ T Lymphocytes: An Effector Cell in Autoimmunity and Infection
by: Carolina Maiumi Shiromizu, et al.
Published: (2018-10-01)

Regulation of γδ T Cell Effector Diversification in the Thymus
by: Morgan E. Parker, et al.
Published: (2020-01-01)

Identification of the Ligands of TCRγδ by Screening the Immune Repertoire of γδT Cells From Patients With Tuberculosis
by: Yuxia Li, et al.
Published: (2019-09-01)

Human γδ T‐cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation
by: Sneha Sant, et al.
Published: (2019-01-01)

Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments
by: Lopes, Noella, et al.
Published: (2022)

REPERTOIRE SELECTION AND EFFECTOR DIFFERENTIATION DURING NKT CELL DEVELOPMENT
by: Gordy, Laura Elizabeth
Published: (2012)

Human macrophage model for selective evaluation of CD8⁺ and γδ⁺ cytotoxic T cell function in tuberculosis
by: Passmore, Jo-Ann Shelley
Published: (2018)

Isolated γδ T cells express natural cytotoxicity receptors
by: Feldmann G, et al.
Published: (2004-07-01)

A Deadly Cargo: Gene Repertoire of Cytotoxic Effector Proteins in the <i>Camelidae</i>
by: Ján Futas, et al.
Published: (2021-02-01)

Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes
by: Narayan, Kavitha, et al.
Published: (2014)

γδ T cells in HIV Disease: Past, Present and Future
by: C. David ePauza, et al.
Published: (2015-01-01)

Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance
by: Martin S. Davey, et al.
Published: (2017-03-01)

Control of CD56 expression and tumor cell cytotoxicity in human Vγ2Vδ2 T cells
by: Focaccetti Chiara, et al.
Published: (2009-09-01)

Differential Roles of the mTOR-STAT3 Signaling in Dermal γδ T Cell Effector Function in Skin Inflammation
by: Yihua Cai, et al.
Published: (2019-06-01)

Altered effector function of peripheral cytotoxic cells in COPD
by: Corne Jonathan M, et al.
Published: (2009-06-01)

MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development.
by: Inga Sandrock, et al.
Published: (2015-01-01)

Human γδ T-Cell Control of Mucosal Immunity and Inflammation
by: Neil E. McCarthy, et al.
Published: (2018-05-01)

TRAIL-Receptor 4 Modulates γδ T Cell-Cytotoxicity Toward Cancer Cells
by: Doaa Tawfik, et al.
Published: (2019-08-01)

Obesity impairs γδ T cell homeostasis and antiviral function in humans.
by: Anne E Costanzo, et al.
Published: (2015-01-01)

A "repertoire for repertoire" hypothesis: repertoires of type three effectors are candidate determinants of host specificity in Xanthomonas.
by: Ahmed Hajri, et al.
Published: (2009-01-01)

Correction: A «Repertoire for Repertoire» Hypothesis: Repertoires of Type Three Effectors are Candidate Determinants of Host Specificity in.
by: Ahmed Hajri, et al.
Published: (2009-01-01)

Cytotoxic effector cells in rat tumours
by: Ferry, B. L.
Published: (1985)

γδ T cells acquire effector fates in the thymus and differentiate into cytokine-producing effectors in a Listeria model of infection independently of CD28 costimulation.
by: Renee M Laird, et al.
Published: (2013-01-01)

Correction: A «Repertoire for Repertoire» Hypothesis: Repertoires of Type Three Effectors are Candidate Determinants of Host Specificity in Xanthomonas
by: Ahmed Hajri, et al.
Published: (2009-01-01)

The BTLA and PD‐1 signaling pathways independently regulate the proliferation and cytotoxicity of human peripheral blood γδ T cells
by: Hyun J. Hwang, et al.
Published: (2021-03-01)

Expression and function of PD-1 in human γδ T cells that recognize phosphoantigens
by: Iwasaki, Masashi
Published: (2011)

Galectin-3 Released by Pancreatic Ductal Adenocarcinoma Suppresses γδ T Cell Proliferation but Not Their Cytotoxicity
by: Daniel Gonnermann, et al.
Published: (2020-06-01)

Presentation of nonpeptide antigens to human γδ T cells
by: Kato, Yu
Published: (2011)

Integral Roles for Integrins in γδ T Cell Function
by: Gabrielle M. Siegers
Published: (2018-03-01)

Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients
by: Corne Jonathan M, et al.
Published: (2010-06-01)

The development of human fetal γδ thymocytes
by: Tieppo, Paola
Published: (2020)

Repertoire analysis of γδ T cells in the chicken enables functional annotation of the genomic region revealing highly variable pan-tissue TCR gamma V gene usage as well as identifying public and private repertoires
by: Robert Dixon, et al.
Published: (2021-10-01)

The Effector Repertoire of the Hop Downy Mildew Pathogen Pseudoperonospora humuli
by: Savithri Purayannur, et al.
Published: (2020-08-01)

The Aging of γδ T Cells
by: Weili Xu, et al.
Published: (2020-05-01)

The Culture of γδT Cells
by: LIAN,JIE, et al.
Published: (2015)

Intratumoral convergence of the TCR repertoires of effector and Foxp3+ CD4+ T cells.
by: Michal Kuczma, et al.
Published: (2010-10-01)

Characterization of Donor Variability for γδ T Cell ex vivo Expansion and Development of an Allogeneic γδ T Cell Immunotherapy
by: Rebecca E. Burnham, et al.
Published: (2020-11-01)

Control of murine cytomegalovirus infection by γδ T cells.
by: Sabrina Sell, et al.
Published: (2015-02-01)

Cannot write session to /tmp/vufind_sessions/sess_hiuvpfpmk8f3d15d1h9k506n2j