Agonist Binding to Chemosensory Receptors: A Systematic Bioinformatics Analysis

Agonist Binding to Chemosensory Receptors: A Systematic Bioinformatics Analysis

Human G-protein coupled receptors (hGPCRs) constitute a large and highly pharmaceutically relevant membrane receptor superfamily. About half of the hGPCRs' family members are chemosensory receptors, involved in bitter taste and olfaction, along with a variety of other physiological processes. H...

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Bibliographic Details
Main Authors: Fabrizio Fierro, Eda Suku, Mercedes Alfonso-Prieto, Alejandro Giorgetti, Sven Cichon, Paolo Carloni
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
G-protein coupled receptor
chemosensory receptor
bitter taste receptor
odorant receptor
bioinformatics
homology modeling
Online Access:http://journal.frontiersin.org/article/10.3389/fmolb.2017.00063/full

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