PU.1 regulates Ccr7 gene expression by binding to its promoter in naïve CD4+ T cells
C‐C chemokine receptor type 7 (CCR7) is expressed on naïve T cells, B cells, and activated dendritic cells (DCs). We previously demonstrated that the transcription factor PU.1/Spi1 positively regulates the expression of CCR7 in DCs. In the present study, we investigated the role of PU.1 in CCR7 expr...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-06-01
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Series: | FEBS Open Bio |
Subjects: | |
Online Access: | https://doi.org/10.1002/2211-5463.12861 |