PU.1 regulates Ccr7 gene expression by binding to its promoter in naïve CD4+ T cells

C‐C chemokine receptor type 7 (CCR7) is expressed on naïve T cells, B cells, and activated dendritic cells (DCs). We previously demonstrated that the transcription factor PU.1/Spi1 positively regulates the expression of CCR7 in DCs. In the present study, we investigated the role of PU.1 in CCR7 expr...

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Bibliographic Details
Main Authors: Takuya Yashiro, Hiromi Takeuchi, Kazumi Kasakura, Chiharu Nishiyama
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12861