A priori estimation of accuracy and of the number of wells to be employed in limiting dilution assays

The use of limiting dilution assay (LDA) for assessing the frequency of responders in a cell population is a method extensively used by immunologists. A series of studies addressing the statistical method of choice in an LDA have been published. However, none of these studies has addressed the point...

Full description

Bibliographic Details
Main Authors: J.G. Chaui-Berlinck, J.A.M. Barbuto
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2000-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000800010