Expression of TLR4 in Non-Small Cell Lung Cancer Is Associated with PD-L1 and Poor Prognosis in Patients Receiving Pulmonectomy

Expression of TLR4 in Non-Small Cell Lung Cancer Is Associated with PD-L1 and Poor Prognosis in Patients Receiving Pulmonectomy

Currently, the effect of inflammation on tumorigenesis and progression has been widely noted. As a member of pattern recognition receptors, toll-like receptor 4 (TLR4) plays a pivotal role in tumor immune microenvironment and has been increasingly investigated. In the present study, we evaluated TLR...

Full description

Bibliographic Details
Main Authors:	Xiubao Ren, Kaiyuan Wang, Jian Wang, Feng Wei, Ning Zhao, Fan Yang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-04-01
Series:	Frontiers in Immunology
Subjects:	toll-like receptor 4 non-small cell lung cancer programmed cell death ligand 1 soluble toll-like receptor 4 tumor microenvironment
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00456/full

Similar Items

Nociceptin Receptor Is Overexpressed in Non-small Cell Lung Cancer and Predicts Poor Prognosis
by: Kaiyuan Wang, et al.
Published: (2019-04-01)

The Fab Fragment of a Humanized Anti-Toll Like Receptor 4 (TLR4) Monoclonal Antibody Reduces the Lipopolysaccharide Response via TLR4 in Mouse Macrophage
by: Binggang Cai, et al.
Published: (2015-10-01)

Escherichia coli Maltose-Binding Protein Induces M1 Polarity of RAW264.7 Macrophage Cells via a TLR2- and TLR4-Dependent Manner
by: Wan Wang, et al.
Published: (2015-04-01)

Avaliação ex vivo da expressão de TLR-2 e TLR-4 em leucócitos de equinos e sua relação com a tolerância à endotoxina
by: Carrenho, Luciana Cristina de Andrade [UNESP]
Published: (2014)

Expressão de TLR2, TLR4 e p-JNK em mucosa de reservatórios ileais de doentes operados por retocolite ulcerativa inespecífica e polipose adenomatosa familiar
by: Paiva, Nielce Maria de, 1962-
Published: (2011)

TOLL-LIKE RECEPTORS (TLR) 2 AND 4 EXPRESSION OF KERATINOCYTES FROM PATIENTS WITH LOCALIZED AND DISSEMINATED DERMATOPHYTOSIS
by: Cristiane Beatriz de Oliveira, et al.
Published: (2015-02-01)

Decreased Toll-like Receptor (TLR) 2 and 4 Expression in Spermatozoa in Couples with Unexplained Recurrent Spontaneous Abortion (URSA)
by: Nasrin Sereshki, et al.
Published: (2019-11-01)

LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4
by: Sheng Han, et al.
Published: (2017-06-01)

TLR‐2 and TLR‐4 expression in monocytes of newborns with late‐onset sepsis
by: Ana C.C. Redondo, et al.
Published: (2014-09-01)

The expression of TLR2 and TLR4 in the kidneys and heart of mice infected with Acanthamoeba spp.
by: Karolina Kot, et al.
Published: (2020-09-01)

Indução diferencial das vias MyD88 e TRIF-dependentes em leucócitos totais de equinos estimulados com LPS de E. coli /
by: Dalmagro, Priscila.
Published: (2016)

Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response
by: Korbinian Bösl, et al.
Published: (2018-05-01)

Contribution à l'étude du mode d'action de deux adjuvants synthétiques ciblant TLR4 : diC14-amidine et CRX-527.
by: Legat, Amandine N. J.
Published: (2010)

TLR-2 and TLR-4 expression in monocytes of newborns with late-onset sepsis,
by: Ana C.C. Redondo, et al.
Published: (2014-10-01)

Dexmedetomidine inhibits the lipopolysaccharide‐stimulated inflammatory response in microglia through the pathway involving TLR4 and NF‐κB
by: Xue‐Yue Zhou, et al.
Published: (2019-12-01)

Study on the effect of miR-217 on sepsis induced lung injury in rats based on TLR4 signaling pathway
by: Li Jin, et al.
Published: (2020-01-01)

TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages
by: Natalya Odoardi, et al.
Published: (2021-05-01)

Effects of oregano essential oil on brain TLR4 and TLR2 gene expression and depressive-like behavior in a rat model
by: Azam Amiresmaeili, et al.
Published: (2018-01-01)

Toll-Like Receptor (TLR)-9 rs352140 Polymorphism is an Immunopathology Protective Factor in Parkinson's Disease in the Northern Iranian Population
by: Niloufar Sadat Miri, et al.
Published: (2020-12-01)

Different engagement of TLR2 and TLR4 in Porphyromonas gingivalis vs. ligature-induced periodontal bone loss
by: Mei LIN, et al.
Published: (2017-08-01)

Mutação inativadora do TLR4 protege contra a obesidade e a restencia a insulina induzidas por dieta hiperlipidica
by: Tsukumo, Daniela Miti Lemos, 1976-
Published: (2008)

Research progress in relationship between TLR4 and nonalcoholic fatty liver disease
by: SHEN Min
Published: (2015-04-01)

Glutamate/NMDA excitotoxicity and HMGB1/TLR4 neuroimmune toxicity converge as components of neurodegeneration
by: Jian Zou, et al.
Published: (2015-03-01)

TLR4 polymorphisms may increase susceptibility to periodontitis in Pg-positive individuals
by: Wenjing Li, et al.
Published: (2019-11-01)

TLR4 em células derivadas da medula óssea é um mediador da resistência à insulina associada à obesidade
by: Razolli, Daniela Soares, 1984-
Published: (2014)

Halo-Substituted Chalcones and Azachalcones-Inhibited, Lipopolysaccharited-Stimulated, Pro-Inflammatory Responses through the TLR4-Mediated Pathway
by: Tzenge-Lien Shih, et al.
Published: (2018-03-01)

Differential Expression of the TLR4 Gene in Pan-Cancer and Its Related Mechanism
by: Jialing Hu, et al.
Published: (2021-09-01)

Decreased monocyte subsets and TLR4-mediated functions in patients with acute severe fever with thrombocytopenia syndrome (SFTS)
by: Cheng Peng, et al.
Published: (2016-02-01)

Association of TLR8 and TLR9 polymorphisms with tuberculosis in a Chinese Han population: a case-control study
by: Ming-Gui Wang, et al.
Published: (2018-11-01)

Inhibition of TLR4 Induces M2 Microglial Polarization and Provides Neuroprotection via the NLRP3 Inflammasome in Alzheimer’s Disease
by: Weigang Cui, et al.
Published: (2020-05-01)

Activation of PPARγ Inhibits TLR4 Signal Transduction Pathway in Melanoma Cancer In Vitro
by: Nasim Dana, et al.
Published: (2020-05-01)

La activación de TLR4 aumenta la expresión de e-selectina y promueve la adhesión del monocito sobre el fibroblasto cardíaco
by: Osorio Sandoval, José Miguel
Published: (2016)

K63-Linked Polyubiquitination on TRAF6 Regulates LPS-Mediated MAPK Activation, Cytokine Production, and Bacterial Clearance in Toll-Like Receptor 7/8 Primed Murine Macrophages
by: Jaya Talreja, et al.
Published: (2018-02-01)

Paeoniflorin Ameliorates Macrophage Infiltration and Activation by Inhibiting the TLR4 Signaling Pathway in Diabetic Nephropathy
by: Yun-xia Shao, et al.
Published: (2019-05-01)

Molecular and cellular dynamics of the Toll-like receptor 4 pathway.
by: Nick eGay, et al.
Published: (2014-10-01)

Impact of asthma, environmental exposures and ethnicity on functional responsiveness to Toll-like receptor (TLR) stimulation in children
by: Lissitsyn, Yuriy V
Published: (2007)

Impact of asthma, environmental exposures and ethnicity on functional responsiveness to Toll-like receptor (TLR) stimulation in children
by: Lissitsyn, Yuriy V
Published: (2007)

Impact of asthma, environmental exposures and ethnicity on functional responsiveness to Toll-like receptor (TLR) stimulation in children
by: Lissitsyn, Yuriy V
Published: (2007)

Selective constraint acting on TLR2 and TLR4 genes of Japanese Rana frogs
by: Quintin Lau, et al.
Published: (2018-05-01)

Preventing Peritoneal Dialysis-Associated Fibrosis by Therapeutic Blunting of Peritoneal Toll-Like Receptor Activity
by: Anne-Catherine Raby, et al.
Published: (2018-11-01)

Cannot write session to /tmp/vufind_sessions/sess_vrlgaebhf9je071s5l49np7nl9