In vivo study of spherical gold nanoparticles: inflammatory effects and distribution in mice.
OBJECTIVES: Gold nanoparticles (AuNPs) of 21 nm have been previously well characterized in vitro for their capacity to target macrophages via active uptake. However, the short-term impact of such AuNPs on physiological systems, in particular resident macrophages located in fat tissue in vivo, is lar...
Main Authors: | Hui Chen, Alisha Dorrigan, Sonia Saad, Dominic J Hare, Michael B Cortie, Stella M Valenzuela |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3585265?pdf=render |
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