In vivo study of spherical gold nanoparticles: inflammatory effects and distribution in mice.

OBJECTIVES: Gold nanoparticles (AuNPs) of 21 nm have been previously well characterized in vitro for their capacity to target macrophages via active uptake. However, the short-term impact of such AuNPs on physiological systems, in particular resident macrophages located in fat tissue in vivo, is lar...

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Bibliographic Details
Main Authors: Hui Chen, Alisha Dorrigan, Sonia Saad, Dominic J Hare, Michael B Cortie, Stella M Valenzuela
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585265?pdf=render