Identification of molecular determinants that govern distinct STIM2 activation dynamics.

Identification of molecular determinants that govern distinct STIM2 activation dynamics.

The endoplasmic reticulum (ER) Ca2+ sensors stromal interaction molecule 1 (STIM1) and STIM2, which connect ER Ca2+ depletion with extracellular Ca2+ influx, are crucial for the maintenance of Ca2+ homeostasis in mammalian cells. Despite the recent progress in unraveling the role of STIM2 in Ca2+ si...

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Bibliographic Details
Main Authors: Sisi Zheng, Guolin Ma, Lian He, Tian Zhang, Jia Li, Xiaoman Yuan, Nhung T Nguyen, Yun Huang, Xiaoyan Zhang, Ping Gao, Robert Nwokonko, Donald L Gill, Hao Dong, Yubin Zhou, Youjun Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2006898

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https://doi.org/10.1371/journal.pbio.2006898

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