Sex-Related Differences in the Physiology, Risk, and Outcomes of Transcatheter Aortic Valve Replacement

Sex-Related Differences in the Physiology, Risk, and Outcomes of Transcatheter Aortic Valve Replacement

Transcatheter aortic valve replacement (TAVR) is a less-invasive alternative to surgical aortic valve replacement (SAVR) for the management of symptomatic severe aortic stenosis in patients with inoperable, high, or intermediate surgical risk. Females undergoing TAVR exhibit distinct physiology and...

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Main Authors: Jennifer Chen MD, Rebecca T. Hahn MD
Format: Article
Language:English
Published: SAGE Publishing 2017-03-01
Series:Gender and the Genome
Online Access:https://doi.org/10.1089/gg.2016.0004
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spelling doaj-02b2d866df6f4cd4bd9703926ed13b1f2020-11-25T03:24:07ZengSAGE PublishingGender and the Genome2470-28972470-29002017-03-01110.1089/gg.2016.0004Sex-Related Differences in the Physiology, Risk, and Outcomes of Transcatheter Aortic Valve ReplacementJennifer Chen MD0Rebecca T. Hahn MD1Columbia University Medical Center/New York–Presbyterian Hospital, New York, New York.Columbia University Medical Center/New York–Presbyterian Hospital, New York, New York.Transcatheter aortic valve replacement (TAVR) is a less-invasive alternative to surgical aortic valve replacement (SAVR) for the management of symptomatic severe aortic stenosis in patients with inoperable, high, or intermediate surgical risk. Females undergoing TAVR exhibit distinct physiology and baseline characteristics from their male counterparts. Although rates of procedural complications are higher, medium-term survival appears better for females than males. These sex-based differences are discussed in depth in this review of TAVR in the female population.https://doi.org/10.1089/gg.2016.0004
collection DOAJ
language English
format Article
sources DOAJ
author Jennifer Chen MD
Rebecca T. Hahn MD
spellingShingle Jennifer Chen MD
Rebecca T. Hahn MD
Sex-Related Differences in the Physiology, Risk, and Outcomes of Transcatheter Aortic Valve Replacement
Gender and the Genome
author_facet Jennifer Chen MD
Rebecca T. Hahn MD
author_sort Jennifer Chen MD
title Sex-Related Differences in the Physiology, Risk, and Outcomes of Transcatheter Aortic Valve Replacement
title_short Sex-Related Differences in the Physiology, Risk, and Outcomes of Transcatheter Aortic Valve Replacement
title_full Sex-Related Differences in the Physiology, Risk, and Outcomes of Transcatheter Aortic Valve Replacement
title_fullStr Sex-Related Differences in the Physiology, Risk, and Outcomes of Transcatheter Aortic Valve Replacement
title_full_unstemmed Sex-Related Differences in the Physiology, Risk, and Outcomes of Transcatheter Aortic Valve Replacement
title_sort sex-related differences in the physiology, risk, and outcomes of transcatheter aortic valve replacement
publisher SAGE Publishing
series Gender and the Genome
issn 2470-2897
2470-2900
publishDate 2017-03-01
description Transcatheter aortic valve replacement (TAVR) is a less-invasive alternative to surgical aortic valve replacement (SAVR) for the management of symptomatic severe aortic stenosis in patients with inoperable, high, or intermediate surgical risk. Females undergoing TAVR exhibit distinct physiology and baseline characteristics from their male counterparts. Although rates of procedural complications are higher, medium-term survival appears better for females than males. These sex-based differences are discussed in depth in this review of TAVR in the female population.
url https://doi.org/10.1089/gg.2016.0004
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AT rebeccathahnmd sexrelateddifferencesinthephysiologyriskandoutcomesoftranscatheteraorticvalvereplacement
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