<i>BTK</i>, <i>NUTM2A,</i> and <i>PRPF19</i> Are Novel <i>KMT2A</i> Partner Genes in Childhood Acute Leukemia

<i>BTK</i>, <i>NUTM2A,</i> and <i>PRPF19</i> Are Novel <i>KMT2A</i> Partner Genes in Childhood Acute Leukemia

Chromosomal rearrangements of the human <i>KMT2A</i>/<i>MLL</i> gene are associated with acute leukemias, especially in infants. <i>KMT2A</i> is rearranged with a big variety of partner genes and in multiple breakpoint locations. Detection of all types of <i>...

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Bibliographic Details
Main Authors: Elena Zerkalenkova, Svetlana Lebedeva, Aleksandra Borkovskaia, Olga Soldatkina, Olga Plekhanova, Grigory Tsaur, Michael Maschan, Aleksey Maschan, Galina Novichkova, Yulia Olshanskaya
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomedicines
Subjects:
pediatric acute leukemia
fusion genes
<i>KMT2A</i>
cytogenetics
NGS
Online Access:https://www.mdpi.com/2227-9059/9/8/924

Internet

https://www.mdpi.com/2227-9059/9/8/924

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