OPG/RANK/RANKL signaling axis in patients with type I diabetes: Associations with parathormone and vitamin D

OPG/RANK/RANKL signaling axis in patients with type I diabetes: Associations with parathormone and vitamin D

Abstract Background Type 1 diabetes (T1D) has been associated with a higher fracture risk due to alterations in bone structure and metabolism. On the other hand, the important role of the RANKL/OPG/RANK signaling axis in bone physiology is well established. The aim of this study was to evaluate the...

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Main Authors: Paraskevi Karalazou, Dimitrios Ntelios, Fani Chatzopoulou, Aikaterini Fragou, Maria Taousani, Konstantina Mouzaki, Assimina Galli-Tsinopoulou, Sofia Kouidou, Georgios Tzimagiorgis
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Italian Journal of Pediatrics
Subjects:
Type 1 diabetes mellitus
Osteoprotegerin
Receptor activator of nuclear factor kappa-B ligand
Receptor activator of nuclear factor kappa-B
Online Access:https://doi.org/10.1186/s13052-019-0748-1

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