| Summary: | Platelet-rich plasma (PRP) has been gaining popularity for degenerative joints because of its success and ease of performing procedure; however, there is a lack of standardized protocols for PRP preparation and clinical applications. Various studies have reported inconsistency and variations in their results. Evidence are inconclusive for its usage in knee osteoarthritis. We conducted a search in the English language literature using keywords such as “Platelet-rich plasma,” “knee joint,” “osteoarthritis,” “techniques,” “growth factors,” or “complications” in PubMed, Embase, and Google Scholar databases. Obtained articles were scrutinized and relevant content was included. This article has reviewed various studies regarding the definition, preparation, concentrates, and clinical application of PRP with respect to degenerative knee joint.
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