Desensitization and treatment with APRIL/BLyS blockade in rodent kidney transplant model.
Alloantibody represents a significant barrier in kidney transplant through the sensitization of patients prior to transplant through antibody mediated rejection (ABMR). APRIL BLyS are critical survival factors for mature B lymphocytes plasma cells, the primary source of alloantibody. We examined the...
Main Authors: | Natalie M Bath, Xiang Ding, Nancy A Wilson, Bret M Verhoven, Brittney A Boldt, Adarsh Sukhwal, Shannon R Reese, Sarah E Panzer, Arjang Djamali, Robert R Redfield |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0211865 |
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