Post-hoc Analysis of Outcome of Intravenous Thrombolysis in Infarcts of Infratentorial Localization in the WAKE-UP Trial

Post-hoc Analysis of Outcome of Intravenous Thrombolysis in Infarcts of Infratentorial Localization in the WAKE-UP Trial

Introduction: In WAKE-UP (Efficacy and Safety of MRI-based Thrombolysis in Wake-Up Stroke), patients with an acute stroke of unknown onset time were randomized to treatment with intravenous alteplase or placebo, guided by MRI.Methods: In this exploratory post-hoc secondary analysis we compared clini...

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Bibliographic Details
Main Authors: Ivana Galinovic, Florent Boutitie, Jochen B. Fiebach, Kersten Villringer, Bastian Cheng, Martin Ebinger, Matthias Endres, Jens Fiehler, Ian Ford, Vincent Thijs, Robin Lemmens, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Claus Z. Simonsen, Pascal Roy, Christian Gerloff, Götz Thomalla
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neurology
Subjects:
infratentorial infarct
infratentorial stroke
intravenous thrombolysis
alteplase
MRI
WAKE-UP
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00983/full

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