The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
The histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast.
Main Authors: | Eun Shik Choi, Youngseo Cheon, Keunsoo Kang, Daeyoup Lee |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-00704-3 |
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