The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3

The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3

The histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast.

Bibliographic Details
Main Authors: Eun Shik Choi, Youngseo Cheon, Keunsoo Kang, Daeyoup Lee
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00704-3
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spelling doaj-02879fff3bb244c6a914ef2df82b912c2021-05-11T07:08:00ZengNature Publishing GroupNature Communications2041-17232017-09-018111010.1038/s41467-017-00704-3The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3Eun Shik Choi0Youngseo Cheon1Keunsoo Kang2Daeyoup Lee3Department of Biological Sciences, Korea Advanced Institute of Science and TechnologyDepartment of Biological Sciences, Korea Advanced Institute of Science and TechnologyDepartment of Microbiology, Dankook UniversityDepartment of Biological Sciences, Korea Advanced Institute of Science and TechnologyThe histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast.https://doi.org/10.1038/s41467-017-00704-3
collection DOAJ
language English
format Article
sources DOAJ
author Eun Shik Choi
Youngseo Cheon
Keunsoo Kang
Daeyoup Lee
spellingShingle Eun Shik Choi
Youngseo Cheon
Keunsoo Kang
Daeyoup Lee
The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
Nature Communications
author_facet Eun Shik Choi
Youngseo Cheon
Keunsoo Kang
Daeyoup Lee
author_sort Eun Shik Choi
title The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
title_short The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
title_full The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
title_fullStr The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
title_full_unstemmed The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
title_sort ino80 complex mediates epigenetic centromere propagation via active removal of histone h3
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-09-01
description The histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast.
url https://doi.org/10.1038/s41467-017-00704-3
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