The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
The histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast.
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-00704-3 |
Summary: | The histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast. |
---|---|
ISSN: | 2041-1723 |