Metabolic syndrome in chronic hepatitis C infection: does it still matter in the era of directly acting antiviral therapy?

TR Lim Centre for Liver Research and NIHR Biomedical Research Unit in Liver Disease, University of Birmingham and Liver and Hepatobiliary Unit, Queen Elizabeth Hospital Birmingham, UK Abstract: Metabolic syndrome is prevalent in patients with hepatitis C virus (HCV) infection. Given the pandemic s...

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Main Author: Lim TR
Format: Article
Language:English
Published: Dove Medical Press 2014-12-01
Series:Hepatic Medicine : Evidence and Research
Online Access:http://www.dovepress.com/metabolic-syndrome-in-chronic-hepatitis-c-infection-does-it-still-matt-peer-reviewed-article-HMER
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spelling doaj-02779ece64b04fa19406d21e15f85d6b2020-11-24T21:06:41ZengDove Medical PressHepatic Medicine : Evidence and Research1179-15352014-12-012014default11311819395Metabolic syndrome in chronic hepatitis C infection: does it still matter in the era of directly acting antiviral therapy?Lim TR TR Lim Centre for Liver Research and NIHR Biomedical Research Unit in Liver Disease, University of Birmingham and Liver and Hepatobiliary Unit, Queen Elizabeth Hospital Birmingham, UK Abstract: Metabolic syndrome is prevalent in patients with hepatitis C virus (HCV) infection. Given the pandemic spread of HCV infection and metabolic syndrome, the burden of their interaction is a major public health issue. The presence of metabolic syndrome accelerates the progression of liver disease in patients with HCV infection. New drug development in HCV has seen an unprecedented rise in the last year, which resulted in better efficacy, better tolerance, and a shorter treatment duration. This review describes the underlying mechanisms and clinical effects of metabolic syndrome in HCV infection, as well as their importance in the era of new directly acting antiviral therapy. Keywords: HCV, genotype 3, metabolic syndrome, steatosis, directly acting antiviral agentshttp://www.dovepress.com/metabolic-syndrome-in-chronic-hepatitis-c-infection-does-it-still-matt-peer-reviewed-article-HMER
collection DOAJ
language English
format Article
sources DOAJ
author Lim TR
spellingShingle Lim TR
Metabolic syndrome in chronic hepatitis C infection: does it still matter in the era of directly acting antiviral therapy?
Hepatic Medicine : Evidence and Research
author_facet Lim TR
author_sort Lim TR
title Metabolic syndrome in chronic hepatitis C infection: does it still matter in the era of directly acting antiviral therapy?
title_short Metabolic syndrome in chronic hepatitis C infection: does it still matter in the era of directly acting antiviral therapy?
title_full Metabolic syndrome in chronic hepatitis C infection: does it still matter in the era of directly acting antiviral therapy?
title_fullStr Metabolic syndrome in chronic hepatitis C infection: does it still matter in the era of directly acting antiviral therapy?
title_full_unstemmed Metabolic syndrome in chronic hepatitis C infection: does it still matter in the era of directly acting antiviral therapy?
title_sort metabolic syndrome in chronic hepatitis c infection: does it still matter in the era of directly acting antiviral therapy?
publisher Dove Medical Press
series Hepatic Medicine : Evidence and Research
issn 1179-1535
publishDate 2014-12-01
description TR Lim Centre for Liver Research and NIHR Biomedical Research Unit in Liver Disease, University of Birmingham and Liver and Hepatobiliary Unit, Queen Elizabeth Hospital Birmingham, UK Abstract: Metabolic syndrome is prevalent in patients with hepatitis C virus (HCV) infection. Given the pandemic spread of HCV infection and metabolic syndrome, the burden of their interaction is a major public health issue. The presence of metabolic syndrome accelerates the progression of liver disease in patients with HCV infection. New drug development in HCV has seen an unprecedented rise in the last year, which resulted in better efficacy, better tolerance, and a shorter treatment duration. This review describes the underlying mechanisms and clinical effects of metabolic syndrome in HCV infection, as well as their importance in the era of new directly acting antiviral therapy. Keywords: HCV, genotype 3, metabolic syndrome, steatosis, directly acting antiviral agents
url http://www.dovepress.com/metabolic-syndrome-in-chronic-hepatitis-c-infection-does-it-still-matt-peer-reviewed-article-HMER
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