Direct squencing from the minimal number of DNA molecules needed to fill a 454 picotiterplate.

Direct squencing from the minimal number of DNA molecules needed to fill a 454 picotiterplate.

The large amount of DNA needed to prepare a library in next generation sequencing protocols hinders direct sequencing of small DNA samples. This limitation is usually overcome by the enrichment of such samples with whole genome amplification (WGA), mostly by multiple displacement amplification (MDA)...

Full description

Bibliographic Details
Main Authors: Mária Džunková, Marc Garcia-Garcerà, Llúcia Martínez-Priego, Giussepe D'Auria, Francesc Calafell, Andrés Moya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24887077/?tool=EBI

Similar Items

Similar Items