Augmented Respiratory–Sympathetic Coupling and Hemodynamic Response to Acute Mild Hypoxia in Female Rodents With Chronic Kidney Disease

Augmented Respiratory–Sympathetic Coupling and Hemodynamic Response to Acute Mild Hypoxia in Female Rodents With Chronic Kidney Disease

Carotid body feedback and hypoxia may serve to enhance respiratory–sympathetic nerve coupling (respSNA) and act as a driver of increased blood pressure. Using the Lewis polycystic kidney (LPK) rat model of chronic kidney disease, we examined respSNA in adult female rodents with CKD and their respons...

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Bibliographic Details
Main Authors: Manash Saha, Qi-Jian Sun, Cara M. Hildreth, Peter G. R. Burke, Jacqueline K. Phillips
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Physiology
Subjects:
female
respiratory sympathetic modulation
chronic kidney disease
hypertension
chemoreflex
hypoxia
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.623599/full

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