Adherence of Helicobacter pylori to the Gastric Mucosa

Adherence of Helicobacter pylori to the Gastric Mucosa

Bacterial adhesion to the intestinal epithelium is a critical initial step in the pathogenesis of many enteric diseases. Helicobacter pylori is a duodenal pathogen that adheres to the gast...

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Main Authors: Marguerite Clyne, Brendan Drumm
Format: Article
Language:English
Published: Hindawi Limited 1997-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1997/149734
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spelling doaj-02570a6476c743bdb7625293bc73b0972020-11-25T00:11:24ZengHindawi LimitedCanadian Journal of Gastroenterology0835-79001997-01-0111324324810.1155/1997/149734Adherence of Helicobacter pylori to the Gastric MucosaMarguerite ClyneBrendan DrummBacterial adhesion to the intestinal epithelium is a critical initial step in the pathogenesis of many enteric diseases. Helicobacter pylori is a duodenal pathogen that adheres to the gastric epithelium and causes gastritis and peptic ulceration. The mechanism by which H pylori causes disease has not yet been elucidated but adherence to the gastric mucosa is thought to be an important virulence determinant of the organism. What is known about adherence of H pylori to the gastric mucosa is summarized. Topics discussed are the mechanism of H pylori adherence; in vitro and in vivo models of H pylori infection; and adherence and potential adhesins and receptors for H pylori.http://dx.doi.org/10.1155/1997/149734
collection DOAJ
language English
format Article
sources DOAJ
author Marguerite Clyne
Brendan Drumm
spellingShingle Marguerite Clyne
Brendan Drumm
Adherence of Helicobacter pylori to the Gastric Mucosa
Canadian Journal of Gastroenterology
author_facet Marguerite Clyne
Brendan Drumm
author_sort Marguerite Clyne
title Adherence of Helicobacter pylori to the Gastric Mucosa
title_short Adherence of Helicobacter pylori to the Gastric Mucosa
title_full Adherence of Helicobacter pylori to the Gastric Mucosa
title_fullStr Adherence of Helicobacter pylori to the Gastric Mucosa
title_full_unstemmed Adherence of Helicobacter pylori to the Gastric Mucosa
title_sort adherence of helicobacter pylori to the gastric mucosa
publisher Hindawi Limited
series Canadian Journal of Gastroenterology
issn 0835-7900
publishDate 1997-01-01
description Bacterial adhesion to the intestinal epithelium is a critical initial step in the pathogenesis of many enteric diseases. Helicobacter pylori is a duodenal pathogen that adheres to the gastric epithelium and causes gastritis and peptic ulceration. The mechanism by which H pylori causes disease has not yet been elucidated but adherence to the gastric mucosa is thought to be an important virulence determinant of the organism. What is known about adherence of H pylori to the gastric mucosa is summarized. Topics discussed are the mechanism of H pylori adherence; in vitro and in vivo models of H pylori infection; and adherence and potential adhesins and receptors for H pylori.
url http://dx.doi.org/10.1155/1997/149734
work_keys_str_mv AT margueriteclyne adherenceofhelicobacterpyloritothegastricmucosa
AT brendandrumm adherenceofhelicobacterpyloritothegastricmucosa
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