Identification of a functional, CRM-1-dependent nuclear export signal in hepatitis C virus core protein.

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide. HCV core protein is involved in nucleocapsid formation, but it also interacts with multiple cytoplasmic and nuclear molecules and plays a crucial role in the development of liver disease and hepatocarcinogenesis....

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Bibliographic Details
Main Authors: Andrea Cerutti, Patrick Maillard, Rosalba Minisini, Pierre-Olivier Vidalain, Farzin Roohvand, Eve-Isabelle Pecheur, Mario Pirisi, Agata Budkowska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22039426/?tool=EBI