Factorial Design as a Tool for the Optimization of PLGA Nanoparticles for the Co-Delivery of Temozolomide and O6-Benzylguanine

Factorial Design as a Tool for the Optimization of PLGA Nanoparticles for the Co-Delivery of Temozolomide and O6-Benzylguanine

Poly(<span style="font-variant: small-caps;">d</span>,<span style="font-variant: small-caps;">l</span>-lactic-<i>co</i>-glycolic) (PLGA) nanoparticles (NPs) have been widely studied for several applications due to their advantageous properties,...

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Bibliographic Details
Main Authors: Maria João Ramalho, Joana A. Loureiro, Manuel A. N. Coelho, Maria Carmo Pereira
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Pharmaceutics
Subjects:
drug delivery
experimental design
fractional factorial design
O6-methylguanine DNA methyltransferase (MGMT) protein
glioblastoma multiforme
Online Access:https://www.mdpi.com/1999-4923/11/8/401

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https://www.mdpi.com/1999-4923/11/8/401

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