β-aminoisobutyric acid attenuates LPS-induced inflammation and insulin resistance in adipocytes through AMPK-mediated pathway

β-aminoisobutyric acid attenuates LPS-induced inflammation and insulin resistance in adipocytes through AMPK-mediated pathway

Abstract Background β-aminoisobutyric acid (BAIBA) is produced in skeletal muscle during exercise and has beneficial effects on obesity-related metabolic disorders such as diabetes and non-alcoholic fatty liver disease. Thus, it is supposed to prevent high fat diet (HFD)-induced inflammation and ins...

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Bibliographic Details
Main Authors: Tae Woo Jung, Hyung Sub Park, Geum Hee Choi, Daehwan Kim, Taeseung Lee
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Biomedical Science
Subjects:
BAIBA
AMPK
NFκB
Inflammation
Insulin resistance
Adipocyte
Online Access:http://link.springer.com/article/10.1186/s12929-018-0431-7

Internet

http://link.springer.com/article/10.1186/s12929-018-0431-7

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