Diabetes mellitus and chronic kidney disease: Possibilities of prediction, early diagnosis, and nephroprotection in the 21st century

The review gives data on the prognostic value of genetic markers when analyzing the risk of chronic kidney disease in diabetes mellitus, those on new possibilities of early diagnosis of diabetic nephropathy using urinary biomarkers (nephrinuria, podocinuria) and proteomic urinalysis at the stage of...

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Main Author: M V Shestakova
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2016-06-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/32022/pdf
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spelling doaj-0209a5675dea4848a3101b268dbb9ca52020-11-25T03:14:09Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422016-06-01886848829037Diabetes mellitus and chronic kidney disease: Possibilities of prediction, early diagnosis, and nephroprotection in the 21st centuryM V ShestakovaThe review gives data on the prognostic value of genetic markers when analyzing the risk of chronic kidney disease in diabetes mellitus, those on new possibilities of early diagnosis of diabetic nephropathy using urinary biomarkers (nephrinuria, podocinuria) and proteomic urinalysis at the stage of normoalbuminuria. The interpretation of the index microalbuminuria in type 2 diabetes is critically analyzed. The nephroprotective properties of novel classes of glucose-lowering drugs, such as incretins and gliflozins, are considered.https://ter-arkhiv.ru/0040-3660/article/viewFile/32022/pdfdiabetes mellituschronic kidney diseasediabetic nephropathyurinary biomarkersurine proteomicsgenetic predictionnephroprotection
collection DOAJ
language Russian
format Article
sources DOAJ
author M V Shestakova
spellingShingle M V Shestakova
Diabetes mellitus and chronic kidney disease: Possibilities of prediction, early diagnosis, and nephroprotection in the 21st century
Терапевтический архив
diabetes mellitus
chronic kidney disease
diabetic nephropathy
urinary biomarkers
urine proteomics
genetic prediction
nephroprotection
author_facet M V Shestakova
author_sort M V Shestakova
title Diabetes mellitus and chronic kidney disease: Possibilities of prediction, early diagnosis, and nephroprotection in the 21st century
title_short Diabetes mellitus and chronic kidney disease: Possibilities of prediction, early diagnosis, and nephroprotection in the 21st century
title_full Diabetes mellitus and chronic kidney disease: Possibilities of prediction, early diagnosis, and nephroprotection in the 21st century
title_fullStr Diabetes mellitus and chronic kidney disease: Possibilities of prediction, early diagnosis, and nephroprotection in the 21st century
title_full_unstemmed Diabetes mellitus and chronic kidney disease: Possibilities of prediction, early diagnosis, and nephroprotection in the 21st century
title_sort diabetes mellitus and chronic kidney disease: possibilities of prediction, early diagnosis, and nephroprotection in the 21st century
publisher "Consilium Medicum" Publishing house
series Терапевтический архив
issn 0040-3660
2309-5342
publishDate 2016-06-01
description The review gives data on the prognostic value of genetic markers when analyzing the risk of chronic kidney disease in diabetes mellitus, those on new possibilities of early diagnosis of diabetic nephropathy using urinary biomarkers (nephrinuria, podocinuria) and proteomic urinalysis at the stage of normoalbuminuria. The interpretation of the index microalbuminuria in type 2 diabetes is critically analyzed. The nephroprotective properties of novel classes of glucose-lowering drugs, such as incretins and gliflozins, are considered.
topic diabetes mellitus
chronic kidney disease
diabetic nephropathy
urinary biomarkers
urine proteomics
genetic prediction
nephroprotection
url https://ter-arkhiv.ru/0040-3660/article/viewFile/32022/pdf
work_keys_str_mv AT mvshestakova diabetesmellitusandchronickidneydiseasepossibilitiesofpredictionearlydiagnosisandnephroprotectioninthe21stcentury
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