GADD45β Regulates Hepatic Gluconeogenesis via Modulating the Protein Stability of FoxO1

GADD45β Regulates Hepatic Gluconeogenesis via Modulating the Protein Stability of FoxO1

Increased hepatic gluconeogenesis is one of the main contributors to the development of type 2 diabetes. Recently, it has been reported that growth arrest and DNA damage-inducible 45 beta (GADD45β) is induced under both fasting and high-fat diet (HFD) conditions that stimulate hepatic gluconeogenesi...

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Bibliographic Details
Main Authors: Hyunmi Kim, Da Som Lee, Tae Hyeon An, Tae-Jun Park, Eun-Woo Lee, Baek Soo Han, Won Kon Kim, Chul-Ho Lee, Sang Chul Lee, Kyoung-Jin Oh, Kwang-Hee Bae
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
GADD45β
gluconeogenesis
FoxO1
protein stability
cAMP signaling
Online Access:https://www.mdpi.com/2227-9059/9/1/50

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