Inhibition of oxidative stress and apoptosis by camel milk mitigates cyclosporine‐induced nephrotoxicity: Targeting Nrf2/HO‐1 and AKT/eNOS/NO pathways

Inhibition of oxidative stress and apoptosis by camel milk mitigates cyclosporine‐induced nephrotoxicity: Targeting Nrf2/HO‐1 and AKT/eNOS/NO pathways

Abstract Cyclosporine (CsA) is a widely used immunosuppressive agent that incurs marked nephrotoxicity in the clinical setting. Thus, there is a need for finding safe/effective agents that can attenuate CsA‐induced kidney injury. Meanwhile, the underlying mechanisms for CsA‐associated nephrotoxicity...

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Bibliographic Details
Main Authors: Hany H. Arab, Ahmed H. Eid, Amany M. Gad, Rania Yahia, Ayman M. Mahmoud, Ahmed M. Kabel
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Food Science & Nutrition
Subjects:
AKT
apoptosis
camel milk
cyclosporine
Nrf2
oxidative stress
Online Access:https://doi.org/10.1002/fsn3.2277

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