The Antimalarial Chloroquine Reduces the Burden of Persistent Atrial Fibrillation

The Antimalarial Chloroquine Reduces the Burden of Persistent Atrial Fibrillation

In clinical practice, reducing the burden of persistent atrial fibrillation by pharmacological means is challenging. We explored if blocking the background and the acetylcholine-activated inward rectifier potassium currents (IK1 and IKACh) could be antiarrhythmic in persistent atrial fibrillation. W...

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Bibliographic Details
Main Authors: Catalina Tobón, Laura C. Palacio, Bojjibabu Chidipi, Diana P. Slough, Thanh Tran, Nhi Tran, Michelle Reiser, Yu-Shan Lin, Bengt Herweg, Dany Sayad, Javier Saiz, Sami Noujaim
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Pharmacology
Subjects:
chloroquine
persistent atrial fibrillation
potassium inward rectifiers
IKACh
IK1
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01392/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01392/full

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