Mast Cell-Derived SAMD14 is a Novel Regulator of the Human Prostate Tumor Microenvironment

Mast Cell-Derived SAMD14 is a Novel Regulator of the Human Prostate Tumor Microenvironment

Mast cells (MCs) are important cellular components of the tumor microenvironment and are significantly associated with poor patient outcomes in prostate cancer and other solid cancers. The promotion of tumor progression partly involves heterotypic interactions between MCs and cancer-associated fibro...

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Bibliographic Details
Main Authors: Linda K. H. Teng, Brooke A. Pereira, Shivakumar Keerthikumar, Cheng Huang, Birunthi Niranjan, Sophie N. Lee, Michelle Richards, Ralf B. Schittenhelm, Luc Furic, David L. Goode, Mitchell G. Lawrence, Renea A. Taylor, Stuart J. Ellem, Gail P. Risbridger, Natalie L. Lister
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
prostate cancer
tumor microenvironment
mast cells
SAMD14
cancer-associated fibroblasts
extracellular matrix
Online Access:https://www.mdpi.com/2072-6694/13/6/1237

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