Targeting of Intracellular TMEM16 Proteins to the Plasma Membrane and Activation by Purinergic Signaling

Anoctamins such as<b> </b>TMEM16A and TMEM16B are Ca<sup>2+</sup>-dependent Cl<sup>−</sup> channels activated through purinergic receptor signaling. TMEM16A (ANO1), TMEM16B (ANO2) and TMEM16F (ANO6) are predominantly expressed at the plasma membrane and are theref...

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Bibliographic Details
Main Authors: Rainer Schreiber, Jiraporn Ousingsawat, Karl Kunzelmann
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/11/4065