AKT signaling mediates IGF-I survival actions on otic neural progenitors.
BACKGROUND: Otic neurons and sensory cells derive from common progenitors whose transition into mature cells requires the coordination of cell survival, proliferation and differentiation programmes. Neurotrophic support and survival of post-mitotic otic neurons have been intensively studied, but the...
Main Authors: | Maria R Aburto, Marta Magariños, Yolanda Leon, Isabel Varela-Nieto, Hortensia Sanchez-Calderon |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3264639?pdf=render |
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