Utilizing ras signaling pathway to direct selective replication of herpes simplex virus-1.
Re-engineering the tropism of viruses is an attractive translational strategy for targeting cancer cells. The Ras signal transduction pathway is a central hub for a variety of pro-oncogenic events with a fundamental role in normal and neoplastic physiology. In this work we were interested in linking...
Main Authors: | Weihong Pan, Vidya Bodempudi, Tuba Esfandyari, Faris Farassati |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2715884?pdf=render |
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