A case of lung adenocarcinoma with a novel CD74‐ROS1 fusion variant identified by comprehensive genomic profiling that responded to crizotinib and entrectinib

A case of lung adenocarcinoma with a novel CD74‐ROS1 fusion variant identified by comprehensive genomic profiling that responded to crizotinib and entrectinib

Abstract ROS1 rearrangements are found in 1–2% of patients with non‐small‐cell lung cancer. The detection of the rearrangements is crucial since clinically effective molecular targeted drugs are available for them. We present a case of lung adenocarcinoma with a previously unknown ROS1‐CD74 fusion v...

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Bibliographic Details
Main Authors: Mizuha Haraguchi Hashiguchi, Takashi Sato, Rinako Watanabe, Junko Kagyo, Tomohiko Matsuzaki, Hideharu Domoto, Terufumi Kato, Yoshiro Nakahara, Tomoyuki Yokose, Yukihiko Hiroshima, Tetsuya Shiomi
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Thoracic Cancer
Subjects:
CD74‐ROS1 fusion variant
crizotinib
entrectinib
lung adenocarcinoma
next‐generation sequencing
Online Access:https://doi.org/10.1111/1759-7714.14093

Internet

https://doi.org/10.1111/1759-7714.14093

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