Differences in the Tongue Features of Primary Dysmenorrhea Patients and Controls over a Normal Menstrual Cycle

Background. The aims of this study were to investigate the relationships between tongue features and the existence of menstrual pain and to provide basic information regarding the changes in tongue features during a menstrual cycle. Methods. This study was conducted at the Kyung Hee University Medic...

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Main Authors: Jihye Kim, Haebeom Lee, Hyunho Kim, Jong Yeol Kim, Keun Ho Kim
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2017/6435702
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spelling doaj-019d002afd054f7b8d77221b215bd6442020-11-25T00:33:33ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882017-01-01201710.1155/2017/64357026435702Differences in the Tongue Features of Primary Dysmenorrhea Patients and Controls over a Normal Menstrual CycleJihye Kim0Haebeom Lee1Hyunho Kim2Jong Yeol Kim3Keun Ho Kim4KM Fundamental Research Division, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon, Republic of KoreaDepartment of Human Informatics of Korean Medicine, Interdisciplinary Programs, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, Republic of KoreaDepartment of Biofunctional Medicine & Diagnostics, College of Korean Medicine, Kyung Hee University, 26-6 Kyungheedae-ro, Dongdaemun-gu, Seoul, Republic of KoreaKM Fundamental Research Division, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon, Republic of KoreaKM Fundamental Research Division, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon, Republic of KoreaBackground. The aims of this study were to investigate the relationships between tongue features and the existence of menstrual pain and to provide basic information regarding the changes in tongue features during a menstrual cycle. Methods. This study was conducted at the Kyung Hee University Medical Center. Forty-eight eligible participants aged 20 to 29 years were enrolled and assigned to two groups according to their visual analogue scale (VAS) scores. Group A included 24 females suffering from primary dysmenorrhea (PD) caused by qi stagnation and blood stasis syndrome with VAS ≥ 4. In contrast, Group B included 24 females with few premenstrual symptoms and VAS < 4. All participants completed four visits (menses-follicular-luteal-menses phases), and the tongue images were taken by using a computerized tongue image analysis system (CTIS). Results. The results revealed that the tongue coating color value and the tongue coating thickness in the PD group during the menstrual phase were significantly lower than those of the control group (P=0.031 and P=0.029, resp.). Conclusions. These results suggest that the tongue features obtained from the CTIS may serve as a supplementary means for the differentiation of syndromes and the evaluation of therapeutic effect and prognosis in PD. Trial Registration. This trial was registered with Clinical Research Information Service, registration number KCT0001604, registered on 27 August 2015.http://dx.doi.org/10.1155/2017/6435702
collection DOAJ
language English
format Article
sources DOAJ
author Jihye Kim
Haebeom Lee
Hyunho Kim
Jong Yeol Kim
Keun Ho Kim
spellingShingle Jihye Kim
Haebeom Lee
Hyunho Kim
Jong Yeol Kim
Keun Ho Kim
Differences in the Tongue Features of Primary Dysmenorrhea Patients and Controls over a Normal Menstrual Cycle
Evidence-Based Complementary and Alternative Medicine
author_facet Jihye Kim
Haebeom Lee
Hyunho Kim
Jong Yeol Kim
Keun Ho Kim
author_sort Jihye Kim
title Differences in the Tongue Features of Primary Dysmenorrhea Patients and Controls over a Normal Menstrual Cycle
title_short Differences in the Tongue Features of Primary Dysmenorrhea Patients and Controls over a Normal Menstrual Cycle
title_full Differences in the Tongue Features of Primary Dysmenorrhea Patients and Controls over a Normal Menstrual Cycle
title_fullStr Differences in the Tongue Features of Primary Dysmenorrhea Patients and Controls over a Normal Menstrual Cycle
title_full_unstemmed Differences in the Tongue Features of Primary Dysmenorrhea Patients and Controls over a Normal Menstrual Cycle
title_sort differences in the tongue features of primary dysmenorrhea patients and controls over a normal menstrual cycle
publisher Hindawi Limited
series Evidence-Based Complementary and Alternative Medicine
issn 1741-427X
1741-4288
publishDate 2017-01-01
description Background. The aims of this study were to investigate the relationships between tongue features and the existence of menstrual pain and to provide basic information regarding the changes in tongue features during a menstrual cycle. Methods. This study was conducted at the Kyung Hee University Medical Center. Forty-eight eligible participants aged 20 to 29 years were enrolled and assigned to two groups according to their visual analogue scale (VAS) scores. Group A included 24 females suffering from primary dysmenorrhea (PD) caused by qi stagnation and blood stasis syndrome with VAS ≥ 4. In contrast, Group B included 24 females with few premenstrual symptoms and VAS < 4. All participants completed four visits (menses-follicular-luteal-menses phases), and the tongue images were taken by using a computerized tongue image analysis system (CTIS). Results. The results revealed that the tongue coating color value and the tongue coating thickness in the PD group during the menstrual phase were significantly lower than those of the control group (P=0.031 and P=0.029, resp.). Conclusions. These results suggest that the tongue features obtained from the CTIS may serve as a supplementary means for the differentiation of syndromes and the evaluation of therapeutic effect and prognosis in PD. Trial Registration. This trial was registered with Clinical Research Information Service, registration number KCT0001604, registered on 27 August 2015.
url http://dx.doi.org/10.1155/2017/6435702
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