Improved success of sparse matrix protein crystallization screening with heterogeneous nucleating agents.
Crystallization is a major bottleneck in the process of macromolecular structure determination by X-ray crystallography. Successful crystallization requires the formation of nuclei and their subsequent growth to crystals of suitable size. Crystal growth generally occurs spontaneously in a supersatur...
Main Authors: | Anil S Thakur, Gautier Robin, Gregor Guncar, Neil F W Saunders, Janet Newman, Jennifer L Martin, Bostjan Kobe |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-10-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2034409?pdf=render |
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