Severe left ventricular systolic dysfunction after permanent pacemaker implantation: Should we pause before upgrading to biventricular pacing?

Left ventricular (LV) systolic dysfunction leading to heart failure (HF) is known to occur after permanent pacemaker implantation (PPI) in a subset of patients. They are often treated by upgradation of the pacemaker to cardiac resynchronisation therapy (CRT). We report a case of progressive LV dysfu...

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Main Authors: Debabrata Bera, Sachin Yalagudri, Soumen Devidutta, Daljeet Kaur Saggu, Zakir Ali, Calambur Narasimhan
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Indian Pacing and Electrophysiology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S0972629219300464
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spelling doaj-017c1df2a7454975a1f2c28833b6e46b2020-11-25T01:29:35ZengElsevierIndian Pacing and Electrophysiology Journal0972-62922019-07-01194161163Severe left ventricular systolic dysfunction after permanent pacemaker implantation: Should we pause before upgrading to biventricular pacing?Debabrata Bera0Sachin Yalagudri1Soumen Devidutta2Daljeet Kaur Saggu3Zakir Ali4Calambur Narasimhan5Dept of Electrophysiology, CARE Hospitals, Hyderabad, IndiaDept of Electrophysiology, CARE Hospitals, Hyderabad, IndiaDept of Electrophysiology, CARE Hospitals, Hyderabad, IndiaDept of Electrophysiology, CARE Hospitals, Hyderabad, IndiaDept of Nuclear Medicine, Basavatarakam Indo-American Cancer Hospital, Hyderabad, IndiaDept of Electrophysiology, CARE Hospitals, Hyderabad, India; Corresponding author. Cardiology CARE Hospital, Hyderabad, India.Left ventricular (LV) systolic dysfunction leading to heart failure (HF) is known to occur after permanent pacemaker implantation (PPI) in a subset of patients. They are often treated by upgradation of the pacemaker to cardiac resynchronisation therapy (CRT). We report a case of progressive LV dysfunction and HF after PPI. Cardiac 18FDG-PET-CT scan revealed abnormal myocardial FDG uptake suggestive of cardiac sarcoidosis (CS). Biopsy from FDG avid lymph node demonstrated non-caseating granuloma. Therapy with steroids resulted in resolution of HF symptoms accompanied by a significant improvement in LV function. Keywords: CRT upgradation, Cardiac sarcoidosis, Pacemaker induced LV dysfunction, Steroidshttp://www.sciencedirect.com/science/article/pii/S0972629219300464
collection DOAJ
language English
format Article
sources DOAJ
author Debabrata Bera
Sachin Yalagudri
Soumen Devidutta
Daljeet Kaur Saggu
Zakir Ali
Calambur Narasimhan
spellingShingle Debabrata Bera
Sachin Yalagudri
Soumen Devidutta
Daljeet Kaur Saggu
Zakir Ali
Calambur Narasimhan
Severe left ventricular systolic dysfunction after permanent pacemaker implantation: Should we pause before upgrading to biventricular pacing?
Indian Pacing and Electrophysiology Journal
author_facet Debabrata Bera
Sachin Yalagudri
Soumen Devidutta
Daljeet Kaur Saggu
Zakir Ali
Calambur Narasimhan
author_sort Debabrata Bera
title Severe left ventricular systolic dysfunction after permanent pacemaker implantation: Should we pause before upgrading to biventricular pacing?
title_short Severe left ventricular systolic dysfunction after permanent pacemaker implantation: Should we pause before upgrading to biventricular pacing?
title_full Severe left ventricular systolic dysfunction after permanent pacemaker implantation: Should we pause before upgrading to biventricular pacing?
title_fullStr Severe left ventricular systolic dysfunction after permanent pacemaker implantation: Should we pause before upgrading to biventricular pacing?
title_full_unstemmed Severe left ventricular systolic dysfunction after permanent pacemaker implantation: Should we pause before upgrading to biventricular pacing?
title_sort severe left ventricular systolic dysfunction after permanent pacemaker implantation: should we pause before upgrading to biventricular pacing?
publisher Elsevier
series Indian Pacing and Electrophysiology Journal
issn 0972-6292
publishDate 2019-07-01
description Left ventricular (LV) systolic dysfunction leading to heart failure (HF) is known to occur after permanent pacemaker implantation (PPI) in a subset of patients. They are often treated by upgradation of the pacemaker to cardiac resynchronisation therapy (CRT). We report a case of progressive LV dysfunction and HF after PPI. Cardiac 18FDG-PET-CT scan revealed abnormal myocardial FDG uptake suggestive of cardiac sarcoidosis (CS). Biopsy from FDG avid lymph node demonstrated non-caseating granuloma. Therapy with steroids resulted in resolution of HF symptoms accompanied by a significant improvement in LV function. Keywords: CRT upgradation, Cardiac sarcoidosis, Pacemaker induced LV dysfunction, Steroids
url http://www.sciencedirect.com/science/article/pii/S0972629219300464
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