| Summary: | Mandibular reconstruction after partial or complete resection is a prerequisite for restoring normal facial aesthetics, articulation and chewing function. We present a clinical case of lower jaw reconstruction in a female patient with acquired extensive bone defect while taking pervitin and desomorphine. Detailed descriptions of the stages of planning and performing surgery, manufacture of an individual endoprosthesis, as well as preoperative preparation of the patient are presented. Clinical and radiological data in the postoperative period were analyzed and an objective assessment of the effectiveness of the technique was given. Adequate restoration of the main functions of the lost organ was achieved thanks to the use of an individual titanium mandibular endoprosthesis with integrated dental implants and a full-arch denture.
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