The role of cytochrome P450 2E1 on ethanol-mediated oxidative stress and HIV replication in human monocyte-derived macrophages

Background: Alcohol consumption is considered to be a major health problem among people living with HIV/AIDS. Our previous reports have shown that ethanol reduced intracellular concentrations of antiretroviral drugs elvitegravir and darunavir in the HIV-1-infected U1 cell line. Ethanol also increase...

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Bibliographic Details
Main Authors: Yuqing Gong, P.S.S. Rao, Namita Sinha, Sabina Ranjit, Theodore J. Cory, Santosh Kumar
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580818301742