Understanding the function and dysfunction of the immune system in lung cancer: the role of immune checkpoints

Understanding the function and dysfunction of the immune system in lung cancer: the role of immune checkpoints

Survival rates for metastatic lung cancer, including non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), are poor with 5-year survivals of less than 5%. The immune system has an intricate and complex relationship with tumorigenesis; a groundswell of research on the immune system is...

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Bibliographic Details
Main Authors: Niki Karachaliou, Maria Gonzalez Cao, Cristina Teixidó, Santiago Viteri, Daniela Morales-Espinosa, Mariacarmela Santarpia, Rafael Rosell
Format: Article
Language:English
Published: China Anti-Cancer Association 2015-06-01
Series:Cancer Biology & Medicine
Subjects:
Lung cancer
immunotherapy
immune checkpoint
program death-ligand 1 (PD-L1)
program death-1 (PD-1)
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/844

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