Novel ligand-based docking; molecular dynamic simulations; and absorption, distribution, metabolism, and excretion approach to analyzing potential acetylcholinesterase inhibitors for Alzheimer's disease

Novel ligand-based docking; molecular dynamic simulations; and absorption, distribution, metabolism, and excretion approach to analyzing potential acetylcholinesterase inhibitors for Alzheimer's disease

Acetylcholinesterase (AChE) plays an important role in Alzheimer's disease (AD). The excessive activity of AChE causes various neuronal problems, particularly dementia and neuronal cell deaths. Generally, anti-AChE drugs induce some serious neuronal side effects in humans. Therefore, this study...

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Bibliographic Details
Main Authors:	Subramaniyan Vijayakumar, Palani Manogar, Srinivasan Prabhu, Ram Avadhar Sanjeevkumar Singh
Format:	Article
Language:	English
Published:	Elsevier 2018-12-01
Series:	Journal of Pharmaceutical Analysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095177917300941

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