Myeloprotection by Cytidine Deaminase Gene Transfer in Antileukemic Therapy

Myeloprotection by Cytidine Deaminase Gene Transfer in Antileukemic Therapy

Gene transfer of drug resistance (CTX-R) genes can be used to protect the hematopoietic system from the toxicity of anticancer chemotherapy and this concept recently has been proven by overexpression of a mutant O6-methylguaninemethyltransferase in the hematopoietic system of glioblastoma patients...

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Bibliographic Details
Main Authors: Nico Lachmann, Sebastian Brennig, Ruhi Phaltane, Michael Flasshove, Dagmar Dilloo, Thomas Moritz
Format: Article
Language:English
Published: Elsevier 2013-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613800541

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