AP-1 Transcription Factors as Regulators of Immune Responses in Cancer

AP-1 Transcription Factors as Regulators of Immune Responses in Cancer

Immune check point blockade therapy has revolutionized the standard of cancer treatment and is credited with producing remarkable tumor remissions and increase in overall survival. This unprecedented clinical success however is feasible for a limited number of cancer patients due to resistance occur...

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Bibliographic Details
Main Authors: Vasileios Atsaves, Vasiliki Leventaki, George Z. Rassidakis, Francois X. Claret
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
AP-1
immune checkpoints
PD-1
CTLA-4
PD-L1
immunotherapy
targeted therapy
transcription factors
Tregs
Online Access:https://www.mdpi.com/2072-6694/11/7/1037

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