The Role of Pontin and Reptin in Cellular Physiology and Cancer Etiology

Pontin (RUVBL1, TIP49, TIP49a, Rvb1) and Reptin (RUVBL2, TIP48, TIP49b, Rvb2) are highly conserved ATPases of the AAA+ (ATPases Associated with various cellular Activities) superfamily and are involved in various cellular processes that are important for oncogenesis. First identified as being upregu...

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Bibliographic Details
Main Authors: Yu-Qian Mao, Walid A. Houry
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmolb.2017.00058/full